Professor in Perioperative Medicine and Critical Care at the University of Southampton and a Consultant in Perioperative Medicine at Southampton University Hospital NHS Foundation trust (UHS).

Denny leads the perioperative medicine service at UHS including a pre-operative CPET service, a pre-operative anaemia service, a surgery school, a shared decision making clinic and prehabilitation. Her clinical and research interests explore the role of exercise in pre-operative risk stratification and pre-operative optimisation to improve surgical outcomes. She established and chairs the National Perioperative Cardiopulmonary Exercise Testing course. She is part of the Fit 4 Surgery research group in Southampton, investigating exercise, psychological and nutritional prehabilitation and is the clinical lead for the multi-centre Wesfit and Safefit Prehabilitation Trials. She is the clinical CI for the INSPIRE trial evaluating inspiratory muscle training before surgery as a means of reducing post-operative complications.

Denny was the research leader, the expedition medical officer and a member of the climbing team on the Caudwell Xtreme Everest Research Expedition, a high altitude field study of hypoxia adaptation. Her PhD thesis involved evaluating exercise capacity at up to 8000m on Mount Everest. (